Some questions and suggestions on the type references of the official nomenclature (IUB) for sialidase(s) and endosialidase. Neuraminidase associated with coliphage E that specifically depolymerizes the Escherichia coli K 1 capsular polysaccharide. Common cleavage pattern of polysialic acid by bacteriophage endosialidases of different properties and origins. Endo- N-acetylneuraminidase associated with bacteriophage particles. Kwiatkowski, B., Boscheck, B., Thicle, H. Use of a bacteriophage-derived endo- N-acetylneuraminidase and an equine antipolysialyl antibody to characterize the polysialyl residues in salmonid fish egg polysialoglycoproteins. Purification and properties of a bacteriophage-induced endo- N-acetylneuraminidase specific for poly-α-2,8-sialosyl carbohydrate units. Hallenbeck, P.C., Vimr, E.R., Yu, F., Bassler, B. Involvement of a long oligosaccharide segment in molecular interactions of polysialic acid. When metastases occurred in endoneuraminidase-N injected animals, they strongly expressed PSA-NCAM. Cleavage of the polysialosyl units of brain glycoproteins by a bacteriophage endosialidase. Endoneuraminidase-N also increased the delay in ascitic formation and decreased the number of lung or liver metastases in the case of intraperitoneal tumors but not in the case of intramuscular tumors. Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, PDB, CAS registry number: 9ġ. An exo-α-sialidase activity is listed as EC 3.2.1.18 exo-α-sialidase. Systematic name: polysialoside 2,8-α-sialosylhydrolaseĬomments: Although the name endo- N-acetylneuraminidase has also been used for this enzyme, this is misleading since its activity is not restricted to acetylated substrates.
Other name(s): endo- N-acylneuraminidase endoneuraminidase endo- N-acetylneuraminidase poly(α-2,8-sialosyl) endo- N-acetylneuraminidase poly(α-2,8-sialoside) α-2,8-sialosylhydrolase endosialidase endo-N with the internal N-acetylneuraminic acid (NeuNAc) units. Reaction: Endohydrolysis of (2→8)-α-sialosyl linkages in oligo- or poly(sialic) acids tracts with a bacteriophage-derived endo-neuraminidase spe. EC 3.2.1.129 Accepted name: endo-α-sialidase
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